自杀意念在大学生抑郁和脑血流变化之间的中介作用：来自fNIRS的证据

doi:10.19988/j.cnki.issn.2095-1159.2026.03.008

心理研究

2026, Vol. 19

Issue (3): 265-273 DOI: 10.19988/j.cnki.issn.2095-1159.2026.03.008

学校心理研究

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自杀意念在大学生抑郁和脑血流变化之间的中介作用：来自fNIRS的证据

张妍¹, 刘国华^1,2, 侯燕^1,3, 曹晓晨¹, 肖强⁴, 郑敏晓^1,5

1 华中科技大学教育科学研究院,武汉 430074;
2 广东海洋大学心理健康教育与咨询中心,湛江 524088;
3 湖北民族大学大学生心理健康教育与咨询中心,恩施 445000;
4 华中科技大学校医院神经内科,武汉 430074;
5 江汉大学教育学院,武汉 430056

The mediating role of suicidal ideation between depression severity and cerebral blood flow changes in college students： Evidence from fNIRS

ZHANG Yan¹, LIU Guohua^1,2, HOU Yan^1,3, CAO Xiaochen¹, XIAO Qiang⁴, ZHENG Minxiao^1,5

1 School of Education, Huazhong University of Science and Technology, Wuhan 430074;
2 Mental Health Education and Counseling Center, Guangdong Ocean University, Zhanjiang 524088;
3 Mental Health Education and Counseling Center for Uncversity Students at Hubei Minzu University, Enshi 445000;
4 Department of Neurology, Huazhong University of Science and Technology Hospital, Wuhan 430074;
5 School of Education, Jianghan University, Wuhan 430056

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摘要为探讨自杀意念在抑郁程度和脑血流动力学变化之间的中介作用,研究选取了92名大学生作为被试。首先,被试完成医院焦虑抑郁量表、自杀意念量表的调查;随后进行言语流畅性任务,同时使用近红外脑功能成像技术记录被试在言语流畅性任务中的脑血流变化情况。结果发现：抑郁组大学生在右背外侧前额叶、左辅助运动区的平均氧合血红蛋白浓度显著低于健康组大学生。此外,自杀意念在抑郁程度与右侧辅助运动区第52通道的平均氧合血红蛋白浓度之间起完全中介作用。本研究表明,抑郁大学生前额叶存在功能损伤,抑郁可通过自杀意念影响前额叶脑血流变化。这些结果提示,在抑郁治疗过程中,应重点关注自杀意念的干预。

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	张妍
	刘国华
	侯燕
	曹晓晨
	肖强
	郑敏晓

关键词 ：抑郁, 自杀意念, 言语流畅性任务, 前额叶

基金资助:中央高校基本科研业务费华中科技大学人文社会科学重大原创性成果培育项目（2026ZDCG001）; 2025年江汉大学社科类一般项目（2025SKYB03）; 2025年湖北本科高校省级教学改革研究项目（2025269）

通讯作者: 郑敏晓,女,讲师,硕士。Email：615907885@qq.com

引用本文:

张妍, 刘国华, 侯燕, 曹晓晨, 肖强, 郑敏晓. 自杀意念在大学生抑郁和脑血流变化之间的中介作用：来自fNIRS的证据[J]. 心理研究, 2026, 19(3): 265-273.
ZHANG Yan, LIU Guohua, HOU Yan, CAO Xiaochen, XIAO Qiang, ZHENG Minxiao. The mediating role of suicidal ideation between depression severity and cerebral blood flow changes in college students： Evidence from fNIRS. Psychological Research, 2026, 19(3): 265-273.

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http://xlyj.magtech.com.cn/CN/10.19988/j.cnki.issn.2095-1159.2026.03.008 或 http://xlyj.magtech.com.cn/CN/Y2026/V19/I3/265

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